Common Heart 
Failure Medications

Explore details on some of the most common
medications used when managing heart failure.

Explore details on some of the most common medications used when managing heart failure

Learn About Medications for Heart Failure

Medications are commonly used to treat heart failure to improve symptoms and slow the progression of the condition. Your heart failure care team will select medications that are best suited to your individual needs. If you feel your heart failure medications are not working or experience any side effects, be sure to talk to your doctor.

Overview of commonly used heart failure medications

An Overview of the Types of Heart Failure Medications

ACE Inhibitors

ACE inhibitors (Angiotensin-Converting Enzyme inhibitors) help relax blood vessels and lower blood pressure, making it easier for the heart to pump blood. They are used in heart failure to reduce the strain on the heart and slow the progression of the disease.

Aldosterone Antagonists

These medications block the effects of aldosterone, a hormone that can lead to fluid retention and worsening heart failure. By reducing fluid buildup, they help lower the strain on the heart and improve symptoms.

ARBs

ARBs (Angiotensin II Receptor Blockers) are similar to ACE inhibitors and are often used as an alternative for those who cannot tolerate ACE inhibitors. They help reduce blood pressure and decrease the workload on the heart, which is crucial for managing heart failure.

ARNIs

ARNIs (Angiotensin Receptor-Neprilysin Inhibitors) combine an ARB with a neprilysin inhibitor to help the heart pump more effectively and reduce fluid buildup. They are specifically used in heart failure to improve outcomes and reduce hospitalization rates.

Blood Thinners

Blood thinners prevent blood clots from forming, which can be important in heart failure patients who have an increased risk of clots due to poor heart function. They help reduce the risk of stroke or heart attack.

Calcium Channel Blockers

These medications relax blood vessels and reduce blood pressure, making it easier for the heart to pump. They are sometimes used in heart failure when other treatments are not effective or when heart rate control is needed.

Digoxin

Digoxin helps the heart pump more strongly and efficiently, improving blood flow and reducing heart failure symptoms like fatigue and shortness of breath. It is used when other treatments are not enough to manage symptoms.

Diuretics

Diuretics, or “water pills,” help the body get rid of excess fluid and salt. This reduces swelling and fluid buildup in the lungs, making it easier for the heart to pump and for patients to breathe.

Hydralazine and Isosorbide Dinitrate

This combination helps dilate blood vessels, reducing the workload on the heart and improving blood flow. It is particularly useful in heart failure patients who do not respond well to other medications, especially in certain racial groups like African Americans.

Ivabradine

Ivabradine slows the heart rate, which reduces the heart’s workload. It is used in heart failure patients with a fast heart rate to improve heart efficiency and reduce symptoms.

Oxygen

Supplemental oxygen is sometimes used in heart failure patients who have low oxygen levels in their blood. It helps relieve shortness of breath and improves the amount of oxygen that reaches the body’s tissues.

Potassium

Potassium supplements may be prescribed to prevent low potassium levels, which can occur due to diuretic use. Proper potassium levels are important for maintaining heart function and avoiding dangerous heart rhythms.

SGLT2 Inhibitors

Originally used for diabetes, SGLT2 inhibitors have been found to benefit heart failure patients by reducing fluid buildup and improving heart function. They help decrease the risk of hospitalization and worsening heart failure.

Statins

Statins lower cholesterol levels and help prevent further heart damage in heart failure patients by reducing the buildup of plaque in the arteries, which can worsen heart conditions.

There are many other types of supplements and medications that may be used based on your particular needs. If you have any questions or concerns regarding your medications, talk to your doctor.  For more information on heart failure medications, visit the American Heart Association Website.

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These materials are not intended to replace your doctor's advice or information. For any questions or concerns you may have regarding the medical procedures, devices and/or your personal health.

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